Table 1.
Mean T1, T2 *, and susceptibility (χ) values with SD calculated over subjects in ROIs for MP2RAGE‐ME, MP2RAGE, and ME‐GRE sequences, with literature reference values
| T1 (s) | (1) | (2) | (3) | (4) | (5) | (6) | T1 (s) | MP2RAGE | MP2RAGEME |
|---|---|---|---|---|---|---|---|---|---|
| WM | 1.15 ± 0.06 | 1.22 ± 0.03 | 1.13 ± 0.10 | 1.22 ± 0.03 | 1.1–1.4 | WM | 1.22 ± 0.01 | 1.19 ± 0.02 | |
| CN | 1.63 ± 0.09 | 1.75 ± 0.06 | 1.68 ± 0.07 | 1.44 ± 0.03 | 1.68 ± 0.06 | 1.6–1.7 | CN | 1.77 ± 0.05 | 1.80 ± 0.08 |
| Putamen | 1.52 ± 0.09 | 1.70 ± 0.07 | 1.64 ± 0.16 | 1.66 ± 0.04 | 1.5–1.7 | Putamen | 1.63 ± 0.04 | 1.63 ± 0.05 | |
| Thalamus | 1.43 ± 0.10 | 1.70 ± 0.04 | Thalamus | 1.59 ± 0.04 | 1.58 ± 0.04 | ||||
| GM | 1.97 ± 0.15/1.87 ± 0.17 | 2.13 ± 0.10 | 1.93 ± 0.15 | 1.80 ± 0.05 | 1.9–2.1 | GM | 1.95 ± 0.04 | 2.00 ± 0.08 | |
| RN | 1.23 ± 0.04 | ~WM | RN | 1.35 ± 0.08 | 1.33 ± 0.07 | ||||
| SN | 1.31 ± 0.04 | SN | 1.37 ± 0.09 | 1.38 ± 0.06 | |||||
| STN | 1.19 ± 0.04 | ~WM | STN | 1.30 ± 0.05 | 1.28 ± 0.04 | ||||
| T2* (ms) | (7) | (8) | (9) | (4) | (5) | (6) | T2 * (ms) | GRE | MP2RAGEME |
| WM | 26.8 ± 1.2 | 25.9 ± 0.8 | 24–27 | WM | 27.1 ± 0.4 | 26.7 ± 0.1 | |||
| CN | 19.9 ± 2.0 | 27.4 ± 1.1 | 28.0 ± 1.9 | 25 | CN | 27.5 ± 1.5 | 27.9 ± 0.5 | ||
| Putamen | 16.1 ± 1.6 | 33.2 ± 1.9 | 20–26 | Putamen | 23.9 ± 1.9 | 24.1 ± 0.6 | |||
| Thalamus | 30.7 ± 1.9 | Thalamus | 27.6 ± 1.1 | 28.1 ± 0.5 | |||||
| GM | 33.2 ± 1.3 | 32.20 ± 1.35 | 32.2 ± 1.45 | 23.7 ± 1.8/37.9 ± 2.2 | 25–33 | GM | 32.8 ± 1.7 | 32.4 ± 0.7 | |
| RN | 17.3 ± 1.5 | 18 | RN | 17.3 ± 3.0 | 16.7 ± 2.4 | ||||
| SN | 13.2 ± 1.0 | SN | 15.6 ± 1.7 | 14.1 ± 0.9 | |||||
| STN | 15.1 ± 1.5 | 6.0–18 | STN | 14.8 ± 1.3 | 16.4 ± 1.4 | ||||
| χ (ppb) | (10) | (11) | (12) | (13) | (5) | (6) | χ (ppb) | GRE | MP2RAGEME |
| WM | −60–20 | WM | −8.9 ± 1.1 | −6.0 ± 0.7 | |||||
| CN | 40 ± 15 | 44 ± 17 | 60 | CN | 32 ± 5 | 26 ± 2 | |||
| Putamen | 25 ± 20 | 38 ± 17 | 20–70 | Putamen | 29 ± 8 | 27 ± 1 | |||
| Thalamus | 8 ± 10 | 45 ± 20 | Thalamus | 13 ± 5 | 10 ± 2 | ||||
| GM | 0–10 | GM | 1.3 ± 1.3 | 1.7 ± 0.2 | |||||
| RN | 65 ± 15 | 100 ± 19 | 28 ± 36 | 80–110 | RN | 74 ± 24 | 68 ± 22 | ||
| SN | 30 ± 10 | 152 ± 30 | 95 ± 34 | SN | 77 ± 22 | 75 ± 11 | |||
| STN | 111 ± 27 | 27 ± 43 | 80–135 | STN | 80 ± 22 | 65 ± 20 |
CN = caudate nucleus; GM = gray matter; ME‐GRE = multi‐echo gradient echo; RN = red nucleus; ROIs = regions of interest; SN = substantia nigra; STN = subthalamic nucleus; WM = white matter. References: 1: (Marques et al., 2010), 2: (Rooney et al., 2007), 3: (Wright et al., 2008), 4: (Metere et al., 2017), 5: (Keuken et al., 2017), (Marques & Norris, 2017), 7: (Peters et al., 2007), 8: (Cohen‐Adad et al., 2012), 9: (Govindarajan et al., 2015), 10: (Sood et al., 2017), 11: (Langkammer et al., 2012), 12: (Khabipova et al., 2014), 13: (Deistung et al., 2013b).