Table 3.

Adjusted Mean Changes in Health-Related Quality of Life over 3 Years Comparing Subjects Aged 70 and Older with Younger Subjects

	Year 1 to Baseline Effect	Year 2 to Baseline Effect	Year 3 to Baseline Effect	Average Effect	P-Value
Domain	Change (Standard Error)
Index of Well-Being
≥70 vs < 18–54	0.51 (0.22)	0.22 (0.29)	0.41 (0.37)	0.38 (0.23)	.10
≥70 vs 55–69	059 (0.23)	0.33 (0.29)	0.35 (0.37)	0.42 (0.22)	.05
Physical Component Summary score
≥70 vs < 18–54	−0.42 (0.70)	−1.44 (0.91)	−0.78 (1.08)	−0.60 (0.72)	.41
≥70 vs 55–69	0.18 (0.70)	−0.71 (0.92)	0.06 (1.06)	−0.16 (0.71)	.83
Mental Component Summary score
≥70 vs o 18–54	−0.38 (0.79)	−0.07 (1.04)	−0.77 (1.28)	−0.41 (0.82)	.62
≥70 vs 55–69	0.38 (0.79)	1.06 (1.05)	−0.59 (1.26)	0.28 (0.80)	.72
Symptom and Problems
≥70 vs <18–54	−0.80 (0.79)	−1.77 (0.98)	−3.03 (1.39)	−1.87 (0.84)	.03
≥70 vs 55–69	−1.41 (0.79)	−0.85 (0.95)	−2.04 (1.38)	−1.43 (0.81)	.08
Effects of Kidney Disease
≥70 vs <18–54	−0.20 (1.32)	−1.37 (1.10)	1.64 (1.97)	0.03 (1.97)	.98
≥70 vs 55–69	−0.64 (1.29)	−0.87 (1.60)	−0.29 (1.96)	−0.60 (1.29)	.64
Sleep
≥70vs <18–54	−4.53 (1.52)	−3.42 (2.13)	−0.71 (2.36)	−2.89 (1.59)	.07
≥70 vs 55–69	−3.20 (1.49)	−2.10 (2.12)	−3.58 (2.34)	−2.96 (1.55)	.06
Cognition Function
≥70 vs <18–54	−2.59 (1.33)	−5.43 (1.78)	−4.77 (2.35)	−4.26 (1.44)	.003
≥70 vs 55–69	−1.30 (1.33)	−3.80 (1.77)	−3.35 (2.38)	−2.82 (1.41)	.05
Patient Satisfaction
≥70 vs <18–54	−0.63 (1.53)	0.17 (1.91)	0.61 (2.35)	0.05 (1.52)	.97
≥ 70 vs 55–69	0.98 (1.49)	3.38 (1.83)	4.56 (2.27)	2.97 (1.43)	.04

Note: Using mixed-effects models adjusting for baseline values for albumin, creatinine, phosphate, Index of Coexistent Disease, duration of dialysis, dose of dialysis, dialysis flux, race, sex, diabetic status, level of education, and mode of questionnaire administration.