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. Author manuscript; available in PMC: 2020 Jul 1.
Published in final edited form as: Anesthesiology. 2019 Jul;131(1):132–147. doi: 10.1097/ALN.0000000000002730

Figure 8:

Figure 8:

Graph presents the concentration response curves for the PRESTO-TANGO assay showing MRG activation by TAN 67, morphine, (DMT)1-DALDA, PZM21, TRV 130, Fentanyl and Buffer. Y-axis expresses the activation in terms of the % of the response observed with TAN67. Best fit log regression curves are presented. The inserted table presents the calculated Log EC50, with 95% confidence intervals for each of the test compounds.