Table 1. Maternal cytokine concentrations at 32 weeks’ gestation.
| Cytokine type | Cytokine, ng/L | Treated, mean±SE (n=179) |
Untreated, mean±SE (n=183) |
Diff (95% CI) | P-value |
|---|---|---|---|---|---|
| Pro-inflammatory | IFN-γ | 6.08±1.84 | 6.89±3.26 | -0.81 (-8.22, 6.60) | 0.83 |
| IL-2 | 2.53±0.07 | 2.49±0.04 | 0.03 (-0.13, 0.20) | 0.68 | |
| IL-12 | 2.72±0.33 | 2.48±0.06 | 0.25 (-0.40, 0.90) | 0.45 | |
| TNF | 2.87±0.27 | 246±0.02 | 0.41 (-0.12, 0.93) | 0.13 | |
| sTNFRI | 143.1±17.4 | 144.7±18.4 | -1.58 (-51.5, 48.3) | 0.95 | |
| sTNFRII | 5.09±0.13 | 8.94±3.91 | -3.85 (-11.7, 3.96) | 0.33 | |
| IL-1 | 2.66±0.16 | 2.83±0.38 | -0.17 (-0.99, 0.65) | 0.68 | |
| IL-6 | 3.80±0.78 | 4.68±1.28 | -0.88 (-3.84, 2.07) | 0.56 | |
| CXCL8 | 3.26±0.46 | 2.98±0.25 | 0.28 (-0.75, 1.31) | 0.59 | |
| Anti-inflammatory | IL-4 | 2.89±0.46 | 2.64±0.14 | 0.25 (-0.69, 1.19) | 0.60 |
| IL-5 | 2.42±0.07 | 2.38±0.06 | 0.05 (-0.13, 0.23) | 0.59 | |
| CXCL9 | 211.5±23.3 | 186.0±21.7 | 25.5 (-37.2, 88.2) | 0.42 | |
| IL-10 | 2.70±0.10 | 3.19±0.15 | -0.48 (-0.84, -0.13) | 0.008 | |
| IL-13 | 3.33±0.27 | 3.00±0.17 | 0.33 (-0.30, 0.95) | 0.31 |
Means and SEs of maternal 32-week cytokine concentrations are presented by treatment group, and mean differences with 95% CI and P-values obtained using linear regression.