Table 1. Pharmacokinetic parameters for danofloxacin in 3-week old vs. 6-month old calves with respiratory disease.

		3-Week Old Calves		6-Month Old Calves
Parameter		Median	Range	Median	Range
AUCinf	hr*μg/ml	29.8*	23.3–49.6	14.2*	10.9–51.4
CL/F	ml/hr/kg	268.6*	161.3–342.2	561.6*	155.6–731.6
T1/2	hr	35.8	24.8–59.4	32.2	18.3–134.9
Cmax	μg/mL	2.2	1.7–4.2	1.5	1.1–10.4
Tmax	hr	2.0	0.8–3.1	1.4	0.4–3.7
Vd/F	L/kg	2.9	1.8–4.0	3.4	0.7–5.9

*Indicates significantly different by t-test (P < 0.05).