Table 3.

Allele and genotype frequencies of all polymorphisms

Gene	SNP	Model		Sample size (%)		Fix-effect model
				ASD cases Number (%) n=529	Controls Number (%) n=480	OR	P value
CACNA1C	rs4765905	Allele	C vs	283 (27)	266 (28)	0.95 (0.78-1.15)	0.63
			G	775 (73)	694 (72)
		Co-dominant	CC vs GG	33(6.2)	35 (7.3)	1.01 (0.78-1.31)	0.8
			CG vs GG	217 (41)	196 (40.8)	1..19 (0.72-1.97)
		Dominant	CC+CG vs GG	250 (47.3)	231 (48.1)	1.04 (0.81-1.33)	0.78
				279 (52.7)	249 (51.9)
		Recessive	CC vs GG+CG	33 (6.2)	35(7.3)	1.18 (0.72-1.93)	0.51
				496 (93.8)	445 (92.7)
		Over dominant	CG vs C+GG	217 (41)	196 (40.8)	0.99 (0.77-1.28)	0.95
				312 (59)	284 (59.2)
	rs4765913	Allele	A vs C	79 (0.07)	85 (0.09)	0.82 (0.59-1.13)	0.22
				974 (93)	859 (91)
		Co-dominant	AA vs TT	34 (6.4)	29 (6)	0.87 (0.51-1.47)	0.46
			AT vs TT	239 (45.2)	251 (52.3)	0.85 (0.66-1.10)
		Dominant	AA+AT vs TT	273(51.6)	229 (47.7)	0.86 (0.67-1.10)	0.22
				256 (48.4)	251 (52.3)
		Recessive	AA vs AT+TT	34 (6.4)	29 (6)	0.94 (0.56-1.56)	0.8
				495 (93.6)	451 (94)
		Over dominant	AT vs TT+AA	239 (45.2)	200 (41.7)	0.87 (0.68-1.11)	0.26
				290 (54.8)	280 (85.3)
	rs1006737	Allele	G vs	234 (22)	246 (26)	1.34 (0.96-1.86)	0.09
			A	824 (78)	714 (74)
		Co-dominant	GG vs AA	28 (5.3)	40 (8.3)	1.10 (0.84-1.43)	0.12
			AG vs AA	178 (33.6)	166 (34.6)	1.68 (1.01-2.80)
		Dominant	GG+AG vs	206 (38.9)	206 (42.9)	1.18 (0.92-1.52)	0.2
			AA	323 (61.1)	274 (57.1)
		Recessive	GG vs	28 (5.3)	40 (8.3)	1.63 (0.99-2.68)	0.05
			AG+AA	501 (94.7)	440 (91.7)
		Over dominant	AG vs	178 (33.6)	166 (34.6)	1.04 (0.80-1.35)	0.75
			GG+AA	351 (66.3)	314 (65.4)