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. 2019 Jun 24;14(6):e0217437. doi: 10.1371/journal.pone.0217437

Fig 6. Extent of freezing during the acquisition FC on day 1, contextual FC on day 2, and the cued FC on day 3.

Fig 6

Chronic treatment with minocycline prevents enhanced fear memory at 8 weeks post MI. Values are means ± SE. For n/group, see bottom of bars. Two-way repeated measures ANOVA for contextual FC: treatment effect F = 1.2, p = 0.33, time-effect F = 8.1, p = 0.006 and treatment × time F = 1.3, p = 0.28. § p <0.05 vs habituation day 1. Two-way repeated measures ANOVA for cued FC: treatment effect F = 4.7, p = 0.02, time-effect F = 17.6, p<0.001, and treatment × time F = 2.1, p = 0.06. *p<0.05 vs pre-tone, † p<0.05 vs other groups.