Table 1: Description of the Sample.
The group analyzed had n=363 people (113 that had stroke within seven years, and 250 that did not). In Table 1, the full sample, and the two groups are compared on demographic characteristics, baseline clinical characteristics, and Neurofilament light chain (NfL) concentration.
| Total Sample (n=363) | Stroke (n=113) | No Stroke (n=250) | |
|---|---|---|---|
| Demographics | |||
| Non-Caucasian (n, %)*** | 92 (25.3%) | 42 (37.2%) | 50 (20.0%) |
| Female (n, %) | 149 (41.0%) | 51 (45.1%) | 98 (39.2%) |
| Age (mean, SD)*** | 62.8 (6.4) | 64.6 (6.8) | 62.0 (6.0) |
| Clinical Characteristics (Baseline) | |||
| Weight in Kg (mean, SD)*** | 91.7 (17.4) | 88.0 (18.4) | 93.3 (16.7) |
| BMI (mean, SD) | 31.9 (5.1) | 31.3 (5.5) | 31.2 (4.9) |
| Systolic BP (mean, SD)*** | 137.3 (18.0) | 144.5 (17.8) | 134.0 (17.1) |
| Years of hypertension (mean, SD) | 10.2 (9.5) | 10.7 (9.5) | 9.9 (9.5) |
| Years of diabetes (mean, SD) | 10.7 (7.4) | 11.7 (7.7) | 10.2 (7.2) |
| Hemoglobin A1C (mean, SD)* | 8.5 (0.9) | 8.7 (1.0) | 8.4 (0.8) |
| Smoke (n, %) | 40 (11.0%) | 11 (9.7%) | 29 (11.6%) |
| Cardiovascular disease history (n, %) | 124 (34.2%) | 39 (34.5%) | 85 (34.0%) |
| Left Ventricular Hypertrophy (n, %) | 5 (1.4%) | 4 (3.5%) | 1 (0.4%) |
| On Hypertensive Medication (n, %) | 300 (82.6%) | 98 (86.7%) | 202 (80.8%) |
| Atrial Fibrillation (n, %) | 3 (0.8%) | 1 (0.9%) | 2 (0.8%) |
| Framingham Score (mean, SD)*** | 9.3 (2.9) | 10.4 (2.7) | 8.8 (2.9) |
| GFR<60ml/min/1.73m2 (n, %) | 36 (9.9%) | 15 (13.4%) | 21 (8.4%) |
| Total cholesterol (mean, SD)* | 184.5 (43.2) | 192.2 (46.0) | 181.1 (41.6) |
| High density lipoprotein (mean, SD) | 41.9 (12.4) | 43.4 (15.1) | 41.2 (10.9) |
| Low density lipoprotein (mean, SD) | 105.2 (33.7) | 110.4 (32.6) | 102.9 (34.0) |
| Triglycerides (mean, SD) | 192.5 (130.2) | 198.8 (166.2) | 189.7 (110.5) |
| Years of hyperlipidemia (mean, SD) | 6.6 (6.0) | 7.2 (6.7) | 6.3 (5.7) |
| Neurofilament light chain (median, IQR) | 15.2 (11.0, 22.8) | 19.8 (14.7, 30.9) | 13.8 (9.9, 19.6) |
SD = standard deviation
***:
p < 0.001
*:
p < 0.05