. Author manuscript; available in PMC: 2019 Jun 24.

Published in final edited form as: Am J Med Genet C Semin Med Genet. 2017 Nov 24;175(4):397–406. doi: 10.1002/ajmg.c.31592

TABLE 2.

Chd7 mutant mouse strains

Strain (s)	Allele	Protein effect	Reference(s)
Wheels (Whl)	Maps to chr 4	NA	Alavizadeh et al., (2001); Bosman et al. (2005); Nolan et al. (1995); Pickard et al., (1995)
Carousel (Crsl)	Not reported	NA	Bosman et al. (2005); Hawker et al., (2005)
Whirligig (Whi)	2918G-A,	W973X	Bosman et al. (2005); Hawker et al., (2005)
Flouncer (Flo)	IVS 27+ 2T-C	Donor splice site; S1864X	Bosman et al. (2005); Pau et al. (2004)
Tornado (Todo)	IVS3 + 2-C	Donor splice site; H549X	Bosman et al. (2005); Kiernan et al. (2002)
Eddy (Edy)	307C-T	Q103X	Bosman et al. (2005); Kiernan et al. (2002)
Leda (Lda)	3195T-A	Y1066X	Bosman et al. (2005); Kiernan et al. (2002)
Orbitron (Obt)	3945T-A	Y1315X	Bosman et al. (2005); Kiernan et al. (2002)
Cyclone (Cycn)	4286T-A	L1429X	Bosman et al. (2005); Kiernan et al. (2002)
Metis (Mt)	IVS 22-2A-G	Acceptor splice site; V1688X	Bosman et al. (2005); Kiernan et al. (2002)
Dizzy (Dz)	5536G-T	E1846X	Bosman et al. (2005); Kiernan et al. (2002)
Volchok (Vlk)	4705T-A	Y1459X	Lenz et al. (2010)
Looper	5690C-A	S1897X	Ogier et al. (2014)
Coa1	2155A-T	K719X	Jiang et al. (2012)
Ome	Exon 2–3 deletion	Loss of protein	Tian et al. (2012)
Chd7^Gt/+	Gene trapped sequences inserted in intron 1	Loss of protein translation due to interrupted ribosomal entry site; expresses p-galactosidase from the Chd7 promoter	Hurd et al. (2007)
Chd7^rrr	Gene trapped sequences inserted in intron 4	Reporter fusion	Randall et al. (2009)
Chd7^xk	Gene trapped sequences inserted in intron 36	Reporter fusion	Randall et al. (2009)
Chd7^flox	Floxed exon 2	Conditional loss of exon 2, containing the ATG start site for transcription	Hurd et al. (2010)
Chd7^fl	Floxed exon 3	Conditional loss of exon 3	Feng et al. (2013)