Table 5.

Hypertension at follow-up, among donors without hypertension at baseline (n=1092)

	Follow-up hypertension
Baseline clinical characteristics	Unadjusted		Adjusted for age and follow-up time		Further adjusted for all clinical characteristics
	OR	P	OR	P	OR	P
Age, per year	1.04	0.003	-	-	-	-
Male	2.52	0.001	2.85	<0.001	-	-
BMI, per kg/m2	1.11	<0.001	1.11	<0.001	-	-
Systolic blood pressure, per 10 mmHg	2.29	<0.001	2.08	<0.001	-	-
Diastolic blood pressure, per 10 mmHg	1.78	0.001	1.64	0.007	-	-
eGFR, per 10 ml/min/1.73 m2	0.81	0.02	0.91	0.39	-	-
Urine Albumin ≥5mg	3.49	<0.001	3.83	<0.001	-	-
Living related donor	1.37	0.25	1.64	0.080	-	-
Nephron Size
Glomerular volume, per SD	1.59	<0.001	1.61	<0.001	1.30	0.07
Cortex volume per glomerulus, per SD	1.46	<0.001	1.35	0.004	1.13	0.35
Tubular cross-sectional area, per SD	1.58	<0.001	1.53	<0.001	1.06	0.73
Nephron number
Nephron number, <5% threshold	1.34	0.59	0.97	0.96	0.84	0.77
CT-based nephrosclerosis
Cortex / Medulla volume, <5% threshold	3.13	0.26	2.63	0.35	2.40	0.40
Largest cyst diameter, >95% threshold	0.91	0.88	0.91	0.88	0.70	0.61
Biopsy-based nephrosclerosis
Globally sclerotic glomeruli >95% threshold	0.54	0.40	0.57	0.44	0.80	0.77
% IF/TA, >95% threshold	2.01	0.10	2.03	0.10	1.40	0.50
Number of IF/TA foci, >95% threshold	2.70	0.00	2.64	0.025	1.86	0.21
Artery luminal stenosis, >95% threshold	4.74	<0.001	4.49	<0.001	4.66	0.002