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. Author manuscript; available in PMC: 2020 Jul 1.
Published in final edited form as: J Cyst Fibros. 2019 Feb 6;18(4):491–500. doi: 10.1016/j.jcf.2019.01.011

Fig. 7.

Fig. 7.

EGCG increases CFTR activity in CF (F508del) macrophages. (A) SPQ assay was performed on WT and CF (F508del) macrophages treated or not with 25 μg/mL EGCG or 5’Aza with or without 1mM3-MA overnight. Values depicted as mean±SEM, are normalized to CF no treatment as 100% functionality. n=4 independent experiments, *p < .05, **p < .01. (B) Western blot of (CFTR) protein of WT and CF macrophages treated with EGCG or vehicle control. Blot is representative of three independent experiments. Densitometry analysis of CFTR (165 kDA) is shown as mean intensities of bands compared to housekeeping (β-actin 42 kDa).