Figure 1.

The proportions of CD11c⁺CD123^– antigen‐presenting cells (APCs) are decreased while CD11c⁺CD123⁺ APCs are increased in latent autoimmune diabetes mellitus in the adult (LADA) compared to type 1 diabetes patients. Proportions of (a) CD11c⁺CD123^–human leucocyte antigen (HLA)‐DR⁺Lin^– APCs in total live cells, (b) CD11c⁺CD123^– APCs among HLA‐DR⁺Lin^– cells, which were gated on HLA‐DR⁺Lin^– cells, (c) CD11c^–CD123⁺HLA‐DR⁺Lin^– plasmacytoid dendritic cells (pDCs) in total live cells, (d) CD11c^–CD123⁺ pDCs among HLA‐DR⁺Lin^– cells, which were gated on HLA‐DR⁺Lin^– cells, (e) CD11c⁺CD123⁺HLA‐DR⁺Lin^– APCs in total live cells and (f) CD11c⁺CD123⁺ APCs among HLA‐DR⁺Lin^– cells, which were gated on HLA‐DR⁺Lin^– cells. The proportions of these cells were determined by using a flow cytometer. HC = healthy controls. One‐way analysis of variance (anova) with Dunnett’s post‐hoc test comparison to patients with LADA was used, n = 13–16/group. *P < 0·05; **P < 0·01.