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. 2019 Jun 24;9:9094. doi: 10.1038/s41598-019-45659-1

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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The stomach mucosa (H&E) and the contours of the electric energy density and the shape of ablated tissue according to the theoretical model. (A) At 10 h after the application of irreversible electroporation, mucosal tissue was seen to be conserved in the nonelectroporated area. (B) The contours predict the ablation area made by the applied electrical energy. The arrow indicates the boundary of the ablated tissue and value of electric field strength is normalized to the critical electric energy density for an ablation of 50 pulses (a). During TUNEL assay, IRE of 2 kV/cm with 50 pulses was applied to the tissue (b).