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. 2019 Jun 24;5:109. doi: 10.1038/s41420-019-0190-6

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 4 — a Expression of LINC01614 in eight BC patients (red box) and adjacent normal tissue (blue box) using qRT-PCR. Data are presented as mean ± S.E., n = 8 for each group. b Expression of LINC01614 in a panel of BC cell lines. Data are presented as normalized delta CT expression value. (c) Heat map clustering of BC (n = 837) and normal (n = 105) breast tissue based on molecular subtypes of BC (HER2 + HR+, HER2+HR−, HER2-HR+, TNBC, and normal). Each row represents expression level of the indicated lncRNA (log2). Expression level of transcriptomes in a single sample is depicted according to the color scale (blue to yellow). (d) Principal component analysis (PCA) for the indicated BC molecular subtypes and normal breast tissue. Expression of LINC01614 in relation to estrogen receptor (ER, e), progesterone receptor (PR, f), and HER2 (g) status. h Expression of LINC01614 in TNBC vs non-TNBC BC patients. i Expression of LINC01614 in the indicated molecular subtype subgroups. j Expression of LINC01614 in the SRP062132 dataset in relation to the indicated molecular subtype. k Expression of LINC01614 in relation to the tumor stages