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. 2019 Jun 24;10(7):496. doi: 10.1038/s41419-019-1731-x

Fig. 4. PSD-95 mediates the Preso regulation of the NO response.

Fig. 4

Mouse cortical neuronal cultures were pretreated with Tat-NR2B9c (10 μM) and ZL006 (10 μM). The cytotoxicity, cell death rate, and NO production in neuronal cultures were analyzed after traumatic neuronal injury (a-c). The data are presented as the mean ± SEM from five experiments. *p < 0.05 vs. Vehicle. Mouse cortical neuronal cultures were transfected with LV-Con and LV-Preso. After transfection, the neuronal cultures were pretreated with Tat-NR2B9c (10 μM) and ZL006 (10 μM). The cytotoxicity, cell death rate, and NO production in neuronal cultures were analyzed at 12 h after TNI (d-f). The data are presented as the mean ± SEM from five experiments. *p < 0.05 vs. LV-Con and #p < 0.05 vs. Vehicle