Table 1.

Parameters used for the bone regeneration model.

Param.	Value	Description
T	12 months	Period of bone regeneration considered in the model
L	30 mm	Length of bone defect/scaffold considered in the model
γ	1%	Hard-loaded engineering strain
D(ρ)	k5(1 − ρ)	Diffusivity of bioactive molecules in the scaffold occupied defect site
$ℂ(\rho ,\sigma ,b)$	ρσ + k6b	Elastic modulus for the scaffold/regenerated bone material composite
k 1	0.1 per month	PCL absorption rate constant
k 2	k3/γ	Generation rate of bioactive molecules
k 3	80 per month	Decay rate of bioactive molecules
k 4	0.25/γ per month	Rate of bone regeneration (healthy individual)
k 5	100(μm)2/s ≈ 260 (mm)2/month	Diffusivity of bioactive molecules without scaffold
k 6	9.0	Relative modulus of bone vs. scaffold