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. 2019 Jun 24;9:9195. doi: 10.1038/s41598-019-45477-5

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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PAX1 inhibits the EGF- and IL-6 mediated kinome. Kinase array revealing PAX1 inhibition of EGF- (A) and IL-6- (B) kinase activity, and signaling, in HeLa cells. (C) Quantitative results of PAX1-inhibited pathway signaling. (D) Western blot confirming decreased ERK1/2 phosphorylation by PAX1, in SiHa cells. GAPDH was used as loading control. Full blots are shown in Supplementary Fig. S3.