TABLE 7.
Significant activated and inhibited upstream regulators.
| Upstream regulator | Molecule type | Activation Z-score | Overlapping P-value |
| ACOX1 | Enzyme | –2.45 | 1.21E-03 |
| MYOD1 | Transcription regulator | –2.41 | 4.70E-03 |
| N-cor | Group | –2.22 | 9.72E-05 |
| CD44 | Other | 2.00 | 6.62E-03 |
| MAPK9 | Kinase | 2.00 | 3.72E-02 |
| CTNNB1 | Transcription regulator | 2.00 | 2.32E-02 |
| IL6 | Cytokine | 2.07 | 3.72E-02 |
| ERK | Group | 2.20 | 3.61E-03 |
| NCOA2 | Transcription regulator | 2.22 | 3.77E-04 |
| TGFB3 | Growth factor | 2.24 | 1.96E-03 |
| CEBPA | Transcription regulator | 2.35 | 3.58E-03 |
| FOXO1 | Transcription regulator | 2.42 | 5.54E-05 |
| PPARA | Ligand-dependent nuclear receptor | 2.54 | 2.41E-05 |
| NFE2L2 | Transcription regulator | 2.58 | 2.32E-03 |