TABLE 2.
Mean and SD of the cortical thickness for each age group according to the diagnostic groups.
| Age group | N | Global | Frontal | Temporal | Parietal | Occipital |
| CN | ||||||
| 50s | 694 | 3.08 (0.10) | 3.13 (0.10) | 3.23 (0.15) | 2.95 (0.14) | 2.72 (0.12) |
| 60s | 1,509 | 3.05 (0.10) | 3.10 (0.11) | 3.22 (0.15) | 2.92 (0.13) | 2.70 (0.12) |
| 70s | 572 | 2.99 (0.12) | 3.04 (0.13) | 3.16 (0.17) | 2.85 (0.14) | 2.63 (0.13) |
| Over-80 | 48 | 2.98 (0.16) | 3.03 (0.16) | 3.14 (0.19) | 2.83 (0.17) | 2.63 (0.16) |
| SMI | ||||||
| 50s | 224 | 3.09 (0.09) | 3.16 (0.10) | 3.28 (0.10) | 2.93 (0.10) | 2.70 (0.11) |
| 60s | 348 | 3.04 (0.10) | 3.11 (0.11) | 3.24 (0.11) | 2.89 (0.11) | 2.65 (0.11) |
| 70s | 247 | 2.96 (0.12) | 3.02 (0.13) | 3.14 (0.15) | 2.80 (0.13) | 2.58 (0.13) |
| Over-80 | 55 | 2.91 (0.13) | 2.98 (0.14) | 3.06 (0.14) | 2.77 (0.15) | 2.54 (0.12) |
| Early-stage aMCI | ||||||
| 50s | 35 | 3.11 (0.09) | 3.18 (0.10) | 3.30 (0.10) | 2.96 (0.08) | 2.73 (0.10) |
| 60s | 96 | 3.03 (0.10) | 3.10 (0.11) | 3.23 (0.11) | 2.88 (0.11) | 2.65 (0.12) |
| 70s | 137 | 2.92 (0.12) | 2.98 (0.14) | 3.08 (0.14) | 2.78 (0.13) | 2.56 (0.12) |
| Over-80 | 37 | 2.85 (0.14) | 2.92 (0.15) | 3.01 (0.16) | 2.71 (0.15) | 2.49 (0.14) |
| Late-stage aMCI | ||||||
| 50s | 62 | 3.03 (0.13) | 3.11 (0.14) | 3.21 (0.16) | 2.87 (0.13) | 2.66 (0.12) |
| 60s | 193 | 2.98 (0.12) | 3.05 (0.12) | 3.15 (0.15) | 2.82 (0.13) | 2.61 (0.12) |
| 70s | 288 | 2.89 (0.13) | 2.96 (0.14) | 3.04 (0.16) | 2.74 (0.13) | 2.54 (0.13) |
| Over-80 | 106 | 2.82 (0.13) | 2.89 (0.14) | 2.95 (0.16) | 2.68 (0.13) | 2.49 (0.14) |
| Very mild AD | ||||||
| 50s | 35 | 2.88 (0.15) | 3.00 (0.13) | 3.05 (0.18) | 2.65 (0.19) | 2.49 (0.20) |
| 60s | 56 | 2.90 (0.16) | 2.99 (0.14) | 3.04 (0.20) | 2.74 (0.19) | 2.53 (0.19) |
| 70s | 125 | 2.84 (0.14) | 2.92 (0.15) | 2.97 (0.17) | 2.70 (0.15) | 2.50 (0.14) |
| Over-80 | 66 | 2.77 (0.15) | 2.85 (0.15) | 2.89 (0.19) | 2.65 (0.17) | 2.45 (0.16) |
| Mild AD | ||||||
| 50s | 43 | 2.78 (0.10) | 2.91 (0.12) | 2.91 (0.15) | 2.55 (0.12) | 2.41 (0.15) |
| 60s | 82 | 2.81 (0.14) | 2.91 (0.13) | 2.93 (0.18) | 2.65 (0.15) | 2.47 (0.17) |
| 70s | 198 | 2.81 (0.15) | 2.90 (0.15) | 2.91 (0.19) | 2.69 (0.17) | 2.50 (0.15) |
| Over-80 | 88 | 2.78 (0.13) | 2.85 (0.13) | 2.87 (0.17) | 2.67 (0.15) | 2.47 (0.15) |
| Moderate to severe AD | ||||||
| 50s | 20 | 2.64 (0.16) | 2.73 (0.20) | 2.79 (0.22) | 2.44 (0.13) | 2.34 (0.18) |
| 60s | 29 | 2.62 (0.17) | 2.74 (0.18) | 2.69 (0.21) | 2.48 (0.20) | 2.32 (0.22) |
| 70s | 54 | 2.66 (0.17) | 2.76 (0.17) | 2.69 (0.22) | 2.55 (0.17) | 2.37 (0.18) |
| Over-80 | 51 | 2.71 (0.18) | 2.79 (0.18) | 2.76 (0.23) | 2.62 (0.19) | 2.41 (0.19) |
Values are N or mean cortical thickness (SD). N, number; SD, standard deviation; CN, cognitively normal; SMI, subjective memory impairment; aMCI, amnestic mild cognitive impairment; AD, Alzheimer’s disease.