Table 1.
GO term enrichment in top upregulated and down regulated genes in PRMT1 knockout mice fed alcohol.
| GO biological process complete | P-value | GO biological process complete | P-value |
|---|---|---|---|
| Downregulated genes | Upregulated genes | ||
| response to drug (GO:0042493) | 1.50E-17 | regulation of cell cycle | 7.87E-16 |
| negative regulation of apoptotic process (GO:0043066) | 7.55E-13 | positive regulation of protein modification process | 3.07E-14 |
| negative regulation of programmed cell death (GO:0043069) | 9.78E-13 | regulation of cell cycle process | 9.95E-14 |
| response to oxygen-containing compound (GO:1901700) | 1.99E-12 | regulation of protein modification process | 2.43E-13 |
| negative regulation of cell death (GO:0060548) | 4.43E-12 | regulation of protein phosphorylation | 2.49E-13 |
| regulation of reactive oxygen species metabolic process (GO:2000377) | 8.15E-12 | regulation of mitotic cell cycle | 7.36E-13 |
| response to chemical (GO:0042221) | 9.17E-12 | regulation of phosphorylation | 7.59E-13 |