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. 2019 Jun 18;13:126. doi: 10.3389/fnbeh.2019.00126

Table 2.

Anxiolytic and antidepressant effects of B. adolescentis in CRS mice.

B. Time in Center of Open Field (%) C. Total Distance of Open Field (cm) D. Total Entries of EPM E. Entries in Open Arms of EPM (%) F. Time in Open Arms of EPM (%) G. Immobility Duration of Tail Suspension Test (%) H. Immobility Duration of Forced swimming test (%)
Con CRS Bif+CRS Con CRS Bif+CRS Con CRS Bif+CRS Con CRS Bif+CRS Con CRS Bif+CRS Con CRS Bif+CRS Con CRS Bif+CRS
5.39 0.32 2.6 1941.64 1658.32 1543.94 15 13 8 20.00 15.38 25.00 21.32 16.32 23.17 22.05 34.53 11.55 5.9 19.33 15.18
5.81 2.84 12.29 1977.99 1462.89 2161.88 19 21 14 26.32 14.29 28.57 25.44 24.48 36.54 2.82 42.82 12.15 8.31 15.45 2.22
8.02 3.78 1.7 2243.67 1696.25 2026.44 23 5 6 21.74 0.00 16.67 23.58 0 17.25 1.35 24.54 32.22 22 29.35 14.88
6.96 0.56 6.97 1854.72 1604.73 2330.81 10 8 20 20.00 12.50 20.00 21.95 15.12 18.94 14.9 22.68 17.27 6.83 35.9 1.03
7.01 3.02 5.51 1936.98 2234.28 2407.91 25 24 10 16.00 16.67 20.00 28.33 18.29 23.19 5.25 22.4 0 9.88 10.32 7.53
4.51 3.76 10.56 2572.29 1902.54 1907.05 6 15 9 16.67 6.67 33.33 22.03 10.54 34 24.03 14.9 12.77 9.62 22.03 3.63
2.46 1.46 4.62 1704.71 1608.22 2393.15 21 10 30 28.57 20.00 23.33 34.26 29.98 20.05 11.58 13.92 13.02 19.22 7.22 24.97
3.71 4.98 6.31 1965.25 1994.96 1623.36 8 22 22 12.50 13.64 9.09 9.35 14.76 5.27 13.52 11.15 6.68 0.62 18.73 7.67
16.11 3.96 2.26 2274.03 1956.94 2101.34 17 11 19 17.65 9.09 15.79 29.42 10 15.74 0.4 33.27 19.03 1.05 7.52 5.53
4.64 3.96 12.06 1529.13 1588.10 2308.45 10 18 27 10.00 11.11 18.52 4.54 11.85 19.57 5 21.32 18.25 7.03 15.78 1.7
5.6 6.53 13.08 2111.62 2502.09 2453.90 20 12 17 25.00 8.33 23.53 26 7.42 22.46 35.6 13.92 3.95 12.27 18.25 21.28
10.18 3.51 2.25 2385.22 1873.10 1532.85 18 19 8 16.67 15.79 25.00 17.55 14.11 26.57 23.95 12.72 9.65 8.64 20.33 3.08
df F P df F P df F P df F P df F P df F P df F P
2,33 4.183 0.024 2,33 1.875 0.169 2,33 0.104 0.901 2,33 9.108 0.001 2,33 3.465 0.043 2,33 3.422 0.045 2,33 5.78 0.007

The mice in groups of Con, CRS and Bif+CRS were given with distilled water (10 mL/kg), distilled water (10 mL/kg), B. adolescentis (0.25×109 CFU/kg) respectively, by gavage for 21 days. N = 12 per group.

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