Table 4.
B. adolescentis reversed the imbalance of the intestinal microflora induced by CRS at the genus level.
A. Shannon index on Genus level | B. PCA on Genus level | D. Proportion of sequences on Genus level: Lactobacillus | E. Proportion of sequences on Genus level: Bacteroides | ||||||||
---|---|---|---|---|---|---|---|---|---|---|---|
Con | CRS | Bif+CRS | NMDS1 | NMDS2 | Con | CRS | Bif+CRS | Con | CRS | Bif+CRS | |
1.29678 | 2.136918 | 1.103383 | Con | −4.3868 | −1.0162 | 0.684 | 0.261 | 0.7448 | 0.0057 | 0.0618 | 0.0125 |
1.106301 | 1.925281 | 1.781085 | −3.218 | −1.3881 | 0.7375 | 0.4001 | 0.5294 | 0.0065 | 0.0188 | 0.0016 | |
1.511226 | 1.984399 | 1.145668 | −4.0307 | −0.46 | 0.6449 | 0.3768 | 0.5958 | 0.0131 | 0.0598 | 0.0006 | |
CRS | −1.8479 | 9.6013 | |||||||||
df | F | P | 7.3032 | −0.9993 | df | F | P | df | F | P | |
2,6 | 7.294 | 0.025 | 8.495 | 2.9059 | 2,6 | 14.997 | 0.005 | 2,6 | 7.488 | 0.023 | |
Bif+CRS | −3.6345 | −0.6355 | |||||||||
−2.0275 | −2.618 | ||||||||||
3.3472 | −5.3902 | ||||||||||
R2 = 0.54811, p = 0.008 |
The mice in groups of Con, CRS and Bif+CRS were given with distilled water (10 mL/kg), distilled water (10 mL/kg), B. adolescentis (0.25×109 CFU/kg) respectively, by gavage for 21 days. N = 3 per group.