Table 6.
Changes in the protein expression of BDNF, IL-1β, TNF-α and Iba1 in the CA1 region of the hippocampus induced by pretreatment with B. adolescentis.
Con | CRS | Bif+CRS | df | F | P | |||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
BDNF | 14,751 | 10,982 | 15,237 | 8,019 | 9,727 | 8,762 | 13,296 | 14,505 | 12,274 | 2,6 | 8.868 | 0.016 |
IL-1β | 3,433 | 4,576 | 5,334 | 8,892 | 7,734 | 9,565 | 4,654 | 5,672 | 6,708 | 2,6 | 15.471 | 0.004 |
TNF-α | 2,829 | 4,075 | 3,323 | 15,288 | 14,169 | 16,283 | 7,956 | 8,932 | 7,249 | 2,6 | 143.837 | 0 |
Iba1 | 6,533 | 7,142 | 5,706 | 10,026 | 8,717 | 10,696 | 5,719 | 6,477 | 7,329 | 2,6 | 15.24 | 0.004 |
The mice in groups of Con, CRS and Bif+CRS were given with distilled water (10 mL/kg), distilled water (10 mL/kg), B. adolescentis (0.25 × 109 CFU/kg), respectively, by gavage for 21 days. N = 3 per group.