Table I.
The effect of cuprizone administration on the body weight of animals.
| Group | Weight (gm) at the start of experiment | Weight (gm) after one week of cuprizone | P-value |
|---|---|---|---|
| Control (no cuprizone injection) | 22.3±0.23 | 23.03±0.21 | >0.05 |
| Cup | 22.2±0.32 | 20.9±0.26 | 0.0039 |
| Cup-Dep | 22.1±0.2 | 21.1±0.2 | 0.0027 |
| Cup-EE | 22±0.24 | 21.1±0.31 | 0.0362 |
| Cup-ED | 22.3±0.17 | 21.3±0.17 | 0.0006 |
Data are presented as mean ± standard error of mean (SEM). Cup, cuprizone; Cup-Dep, cuprizone underwent depression; Cup-EE, cuprizone housed in EE; Cup-ED, cuprizone housed in EE and underwent depression.