Table IV.
Hematopoiesis in MMS350-treated long-term bone marrow cultures: Day-7 Colony Forming Unit-Granulocyte, Erythrocyte, Monocyte, Megakaryocyte. Analysis of day-7 colony counts at each week, where data are summarized as mean±standard deviation, n is the sample size, and p-value for comparison between the two groups with the two-sided two sample t-test. Significant p-Values are shown in bold.
Group | 1 | 2 | 3 | 4 | 5 | 6 | 7 |
---|---|---|---|---|---|---|---|
Control | 16.67±2.31 (n=3) | 20.00±3.46 (n=3) | 52.67±1.15 (n=3) | 10.67±1.15 (n=3) | 18.33±2.08 (n=3) | 26.67±3.06 (n=3) | 23.00±1.00 (n=3) |
MMS350 | 21.67±2.08 (n=3) | 17.00±2.65 (n=3) | 18.00±2.00 (n=3) | 11.33±2.08 (n=3) | 13.00±1.00 (n=3) | 30.67±3.06 (n=3) | 30.00±3.00 (n=3) |
p- Value | 0.0495 | 0.2991 | <0.0001 | 0.6530 | 0.0161 | 0.1841 | 0.0186 |