Table VII.

Relative gene expression in bone marrow stromal cell line maintained in MMS350. Data summary and group comparisons for the expression of the 30 genes in B6 stromal+/+ cells with or without MMS350, where n is the number of repetitions, p-Value for the comparison between the group with permanent MMS350 and the group without. Data are from Figure 3.

		Continuous MMS350
Gene name	Gene symbol	With	Without	p-Value
NFKb	Nfkb	21.29±2.53 (n=3)	1.25±1.09 (n=3)	0.0002
TGFb	Tgfb	10.15±9.28 (n=4)	0.25±0.017 (n=3)	0.1224
SP1	Sp1	−0.48±14.39 (n=4)	0.13±0.13 (n=3)	0.9374
API	Ap1	43.86±20.20 (n=4)	0.93±1.10 (n=3)	0.0236
IL-1a	Il1a	81.48±14.52 (n=4)	0.81±1.13 (n=3)	0.0015
Gadd45	Gadd45	32.72±5.45 (n=4)	0.15±0.20 (n=5)	0.0013
MnSOD	Sod2	46.50±9.57 (n=4)	0.35±0.27 (n=5)	0.0024
NRF2	Nrf2	−12.17±7.35 (n=4)	0.26±0.26 (n=3)	0.0429
P53	P53	36.95±1.59 (n=3)	0.87±1.22 (n=3)	<0.0001
P21	P21	−7.84±16.04 (n=4)	0.66±0.84 (n=5)	0.3671
Rad51	Rad51	77.56±18.73 (n=4)	0.12±0.11 (n=3)	0.0037
PGC-1A	Pvc1a	−37.03±10.69 (n=4)	0.19±0.08 (n=3)	0.0061
TLR-4	Tlr4	−19.03±14.07 (n=4)	0.05±0.03 (n=3)	0.0730
TNF-A	Tnfa	109.69±31.44 (n=4)	1.70±1.35 (n=3)	0.0062
vWF	Vwf	−37.38±14.72 (n=3)	0.49±0.28 (n=3)	0.0468
fgf1	Fgf1	−35.92±20.04 (n=4)	0.39±0.50 (n=3)	0.0361
vegfa	Vegfa	−6.72±53.19 (n=4)	0.16±0.16 (n=3)	0.8127
ctgf	Ctgf	53.95±23.04 (n=3)	0.10±0.10 (n=3)	0.0560
il6	Il6	−39.43±8368 (n=4)	0.04±0.02 (n=3)	0.0028
lox	Lox	12.85±60.88 (n=4)	0.30±0.33 (n=3)	0.7078
tlr1	Tlr1	−75.01±10.16(n=3)	2.36±1.66 (n=3)	0.0002
tlr2	Tlr2	−36.33±20.60 (n=3)	0.40±0.34 (n=3)	0.0908
tlr5	Tlr5	−59.00±18.84 (n=4)	0.47±0.36 (n=3)	0.0080
tlr6	Tlr6	−82.12±9.83 (n=4)	0.57±0.40 (n=3)	0.0004
tlr7	Tlr7	−50.12±12.08 (n=4)	1.48±0.43	0.0033