Time-kill curves evaluating ORI (0.06 mg/liter, 1/16 MIC) and ampicillin (4 and 8 mg/liter) alone or in various combinations (A) or oritavancin with rifampin (2 mg/liter, 1/4 MIC) and oritavancin, rifampin, and ampicillin (4 mg/liter) alone or in various combinations (B), as shown against the clinical VRE isolate. Data plotted are means ± SEM and represent the mean of triplicates. ORI, oritavancin; RIF, rifampin; AMP, ampicillin. (C) Relative activities over 8 h of ORI (0.12 mg/liter, 1/8 MIC) and ampicillin (4 mg/liter) with or without cathelicidin LL-37 (2 μM). Each experiment was done in triplicate and independently repeated three times.