TABLE 1.
Genotyped β-lactamases and combinations in ESBL-positive isolates of E. coli (n = 114) and K. pneumoniae (n = 151), excluding non-ESBL SHVs and TEMs
| β-Lactamasea | No. of isolates |
|||||
|---|---|---|---|---|---|---|
| No additional β-lactamase |
Additional CTX-M β-lactamase |
Additional SHV β-lactamase |
||||
| E. coli | K. pneumoniae | E. coli | K. pneumoniae | E. coli | K. pneumoniae | |
| CTX-M | 96 | 75 | 2 | 4c | ||
| SHV | 4 | 10 | ||||
| TEM | 1 | 1 | ||||
| KPC | 2 | 30 | 1b | 6d | 9b | |
| VIM | 1 | 1 | ||||
| AmpC | 2 | 4 | 1 | 1 | ||
| OXA | 12 | 2 | ||||
a
The β-lactamase genes identified included CTX-M-1, -9, -14, -15, -22, -27, -32, -61, -55, and -181; SHV-2, -2A, -7, -12, and -28; TEM-24 and -28; KPC-2 and -3; VIM-1; and the AmpCs CMY-type, ACC-1, DHA-7; and OXA-48 and -232.
b
One isolate with an additional AmpC.
c
Two isolates with an additional OXA.
d
One isolate with an additional OXA.