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. 2019 Jun 24;63(7):e00271-19. doi: 10.1128/AAC.00271-19

TABLE 1.

Representative MIC values against colistin-resistant clinical isolatesa

Strain MIC (μg/ml)
CST PMB TGC CAZ FEP ATM MEM AMK LVX NIT
E. coli 08-85 8 8 0.25 0.5 32 64 ≤0.03 4 32 64
E. coli 13-43 8 8 1 2 8 64 ≤0.03 4 64 128
E. coli 13-66 8 8 1 2 4 16 ≤0.03 2 64 128
E. coli 13-68 8 8 0.5 1 8 4 ≤0.03 32 8 128
E. coli H67 4 4 0.25 64 128 64 4 2 16 256
K. pneumoniae 09-20 16 16 2 1 0.5 0.5 ≤0.03 >1,024 32 256
K. pneumoniae H04 32 32 1 >256 8 32 2 256 32 ≥512
E. cloacae D01 256 256 2 256 2 64 1 2 0.125 64
E. cloacae L09 32 32 1 >256 32 64 4 16 32 256
E. cloacae R31 64 128 0.5 1 0.064 64 1 2 1 64
a

CST, colistin; PMB, polymyxin B; TGC, tigecycline; CAZ, ceftazidime; FEP, cefepime; ATM, aztreonam; MEM, meropenem; AMK, amikacin; LVX, levofloxacin; NIT, nitrofurantoin. According to CLSI supplement M100 (28th edition), breakpoints for resistance are listed as follows: CST/PMB/MEM, 4 μg/ml; LVX, 8 μg/ml; CAZ/FEP/ATM, 16 μg/ml; AMK, 64 μg/ml; NIT, 128 μg/ml (27).