TABLE 1.
Strain | MIC (μg/ml) |
|||||||||
---|---|---|---|---|---|---|---|---|---|---|
CST | PMB | TGC | CAZ | FEP | ATM | MEM | AMK | LVX | NIT | |
E. coli 08-85 | 8 | 8 | 0.25 | 0.5 | 32 | 64 | ≤0.03 | 4 | 32 | 64 |
E. coli 13-43 | 8 | 8 | 1 | 2 | 8 | 64 | ≤0.03 | 4 | 64 | 128 |
E. coli 13-66 | 8 | 8 | 1 | 2 | 4 | 16 | ≤0.03 | 2 | 64 | 128 |
E. coli 13-68 | 8 | 8 | 0.5 | 1 | 8 | 4 | ≤0.03 | 32 | 8 | 128 |
E. coli H67 | 4 | 4 | 0.25 | 64 | 128 | 64 | 4 | 2 | 16 | 256 |
K. pneumoniae 09-20 | 16 | 16 | 2 | 1 | 0.5 | 0.5 | ≤0.03 | >1,024 | 32 | 256 |
K. pneumoniae H04 | 32 | 32 | 1 | >256 | 8 | 32 | 2 | 256 | 32 | ≥512 |
E. cloacae D01 | 256 | 256 | 2 | 256 | 2 | 64 | 1 | 2 | 0.125 | 64 |
E. cloacae L09 | 32 | 32 | 1 | >256 | 32 | 64 | 4 | 16 | 32 | 256 |
E. cloacae R31 | 64 | 128 | 0.5 | 1 | 0.064 | 64 | 1 | 2 | 1 | 64 |
CST, colistin; PMB, polymyxin B; TGC, tigecycline; CAZ, ceftazidime; FEP, cefepime; ATM, aztreonam; MEM, meropenem; AMK, amikacin; LVX, levofloxacin; NIT, nitrofurantoin. According to CLSI supplement M100 (28th edition), breakpoints for resistance are listed as follows: CST/PMB/MEM, 4 μg/ml; LVX, 8 μg/ml; CAZ/FEP/ATM, 16 μg/ml; AMK, 64 μg/ml; NIT, 128 μg/ml (27).