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. 2019 Jun 24;63(7):e00279-19. doi: 10.1128/AAC.00279-19

TABLE 2.

Preliminary and final Cox proportional hazards modelsa

Factor Preliminary model
Final model
Hazard ratio 95% CI Adjusted hazard ratio 95% CI
New-generation FQs 1.91 1.14–3.21 2.16 1.28–3.64
Lung diseaseb 0.51 0.28–0.96
Cancer 1.60 0.81–3.15
AMG resistance 1.38 0.80–2.39
Concurrent anti-TB drugs
    Isoniazid 0.34 0.16–0.75 0.35 0.16–0.78
    Clofazimine 2.97 1.63–5.43 2.51 1.37–4.60
    Linezolid 1.77 0.89–3.51
a

AMG, aminoglycoside; CI, confidence interval; FQs, fluoroquinolones; TB, tuberculosis. Values in boldface indicate P values of <0.05.

b

Including chronic obstructive pulmonary disease, asthma, and bronchiectasis.