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. 2019 Jun 24;63(7):e02505-18. doi: 10.1128/AAC.02505-18

TABLE 3.

MICs for the synergistically interacting antifungal and nonantifungal ophthalmic agents natamycin and timolol

Strain MIC (μg/ml) of each agent alone
MIC (μg/ml) of each agent in the combination
FICI Avg FICI
Natamycin Timolol Natamycin Timolol
F. solani
    132.02 16 >6,800 8 425 0.53 0.52
     4 3,400 0.50
    06-0487 32 >6,800 16 213 0.52 0.45
     8 1,700 0.38
    06-0330 32 >6,800 16 213 0.50 0.41
     8 850 0.31
    06-0133 32 >6,800 16 53 0.50 0.41
     8 850 0.31
    06-0111 32 >6,800 16 213 0.52 0.52
    06-0110 32 >6,800 16 53 0.50 0.41
8 850 0.31
F. oxysporum
    06-0342 32 >6,800 16 213 0.52 0.41
     8 850 0.31
    06-0197 16 >6,800 8 53 0.50 0.44
4 1,700 0.38