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Biofilm and cell viability reduction from treatment with TOB and/or RFX. (A) Biofilms were grown for 24 h in a 96-well plate and then treated with TOB, RFX, or TOB and RFX at a concentration of 3× MIC. (B) Biofilms were grown for 24 h in a 96-well plate and then treated with TOB, RFX, or TOB and RFX at concentration of 3× MIC. Two-way ANOVA analysis was used with statistical significance set as a P value of <0.01 (****, P < 0.0001; **, P < 0.001; *, P < 0.01).
