Barbaro 2018.
| Methods | Randomised controlled trial conducted at 14 treatment centers based in the USA, UK, and India | |
| Participants | Participants over the age of 18 years who were eligible for anterior temporal lobectomy (ATL) to treat pharmaco‐resistant unilateral mesial temporal lobe epilepsy (MRI evidence of concordant unilateral hippocampal sclerosis without significant secondary cortical lesions and at least 3 focal‐onset seizures with impairment of consciousness occurred during stable anticonvulsant administration documented over three months), | |
| Interventions | Randomisation to stereotactic radiosurgery (SRS, n = 31 analysed) or anterior temporal lobectomy (ATL, n = 27 analysed); a total of 63 participants were randomised and five withdrew before surgery. | |
| Outcomes | Seizure remission outcome is defined by the seizure‐free (defined as at least Engel scale IB) rate between 25 and 36 months. Adverse events Verbal memory and quality of life (not relevant to this review). |
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| Notes | ||