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. 2019 Jun 25;2019(6):CD010541. doi: 10.1002/14651858.CD010541.pub3

Barbaro 2018.

Methods Randomised controlled trial conducted at 14 treatment centers based in the USA, UK, and India
Participants Participants over the age of 18 years who were eligible for anterior temporal lobectomy (ATL) to treat pharmaco‐resistant unilateral mesial temporal lobe epilepsy (MRI evidence of concordant unilateral hippocampal sclerosis without significant secondary cortical lesions and at least 3 focal‐onset seizures with impairment of consciousness occurred during stable anticonvulsant administration documented over three months),
Interventions Randomisation to stereotactic radiosurgery (SRS, n = 31 analysed) or anterior temporal lobectomy (ATL, n = 27 analysed); a total of 63 participants were randomised and five withdrew before surgery.
Outcomes Seizure remission outcome is defined by the seizure‐free (defined as at least Engel scale IB) rate between 25 and 36 months.
Adverse events
Verbal memory and quality of life (not relevant to this review).
Notes