TABLE 5.
Estimated mean difference in blood pressure associated with 2SD higher intakes of low-fat dairy products and low-fat milk in Western INTERnational study on MAcro/micronutrients and blood Pressure subcohorts
| SBP | DBP | ||||
|---|---|---|---|---|---|
| Difference (95% Cl) | Difference (95% Cl) | ||||
| Model | mmHg | P | mmHg | P | |
| Excluding participants with a diagnosis of hypertension and users of antihypertensive drugs (n = 1836)a | |||||
| Low−fat dairy products | |||||
| Model 1 | −3.61 (−5.68 to −1.55) | 0.001 | −2.11 (−3.60 to −0.63) | 0.005 | |
| Model 2 | −2.60 (−4.68 to −0.53) | 0.01 | −1.53 (−3.03 to −0.03) | 0.05 | |
| Model 3 | −2.61 (−4.71 to −0.53) | 0.02 | −1.61 (−3.12 to −0.10) | 0.04 | |
| Model 3c | −3.20 (−4.30 to −1.09) | 0.003 | −1.99 (−3.50 to −0.44) | 0.01 | |
| Low−fat milk | |||||
| Model 1 | −3.53 (−4.69 to −1.52) | 0.001 | −1.92 (−3.35 to −0.49) | 0.01 | |
| Model 2 | −2.68 (−3.68 to −0.68) | 0.01 | −1.42 (−2.85 to 0.02) | 0.05 | |
| Model 3 | −3.08 (−4.22 to −0.94) | 0.01 | −1.60 (−3.15 to −0.06) | 0.04 | |
| Model 3c | −3.53 (−4.66 to −1.37) | 0.001 | −1.88 (−3.41 to −0.31) | 0.02 | |
| Nonhypertensive participants | (n = 1755)b | ||||
| Low−fat dairy products | |||||
| Model 1 | −2.11 (−3.98 to −0.25) | 0.03 | −1.33 (−2.72 to −0.11) | 0.07 | |
| Model 2 | −1.18 (−3.05 to −0.11) | 0.04 | −0.76 (−2.18 to 0.36) | 0.28 | |
| Model 3 | −1.13 (−3.05 to −0.08) | 0.04 | −0.45 (−1.25 to 0.36) | 0.28 | |
| Model 3c | −1.67 (−2.54 to −0.31) | 0.03 | −0.59 (−1.40 to −0.23) | 0.04 | |
| Low−fat milk | |||||
| Model 1 | −2.44 (−3.22 to −0.65) | 0.01 | −1.44 (−2.79 to −0.09) | 0.04 | |
| Model 2 | −2.38 (−3.28 to −0.42) | 0.02 | −0.97 (−2.33 to 0.38) | 0.16 | |
| Model 3 | −2.34 (−3.25 to −0.44) | 0.02 | −1.37 (−2.82 to 0.08) | 0.06 | |
| Model 3c | −2.70 (−3.61 to 0.79) | 0.01 | −1.60 (−3.05 to −0.15) | 0.03 | |
| Excluding participants with cardiovascular diseases or diabetes mellitus (n= 1570)c | |||||
| Low−fat dairy products | |||||
| Model 1 | −2.67 (−3.50 to −0.86) | 0.005 | −1.31 (−2.70 to 0.13) | 0.07 | |
| Model 2 | −1.82 (−3.78 to −0.10) | 0.04 | −0.86 (−2.30 to 0.59) | 0.25 | |
| Model 3 | −1.84 (−3.77 to −0.13) | 0.04 | −0.99 (−2.49 to 0.48) | 0.18 | |
| Model 3c | −2.31 (−3.30 to −0.32) | 0.02 | −1.33 (−2.80 to 0.14) | 0.07 | |
| Low−fat milk | |||||
| Model 1 | −2.66 (−3.52 to −0.81) | 0.005 | −1.20 (−2.57 to 0.18) | 0.09 | |
| Model 2 | −1.96 (−3.82 to −0.11) | 0.04 | −0.91 (−2.30 to 0.48) | 0.20 | |
| Model 3 | −2.34 (−3.35 to −0.37) | 0.02 | −1.12 (−2.60 to 0.37) | 0.14 | |
| Model 3c | −2.68 (−3.67 to −0.69) | 0.01 | −1.35 (−2.84 to 0.14) | 0.07 | |
CI, confidence interval.
2SD (g/1000 kcal) low-fat dairy products = 204, low-fat milk = 136.
2SD (g/1000 kcal) low-fat dairy products = 206, low-fat milk = 136.
2SD (g/1000 kcal) low-fat dairy products = 202, low-fat milk = 132. Adjusted as footnote in Table 2, except Model 3 in low-fat milk, where it was adjusted for variables in Model 2 with whole-fat milk (g/1000 kcal).