Skip to main content
. Author manuscript; available in PMC: 2020 Jun 1.
Published in final edited form as: Prostate. 2019 Apr 18;79(9):980–993. doi: 10.1002/pros.23809

Figure 1. Histologic Changes in the Male NOD Mouse Prostate.

Figure 1.

A) NOD mice exhibit a range of prostatic phenotypes including areas that have normal prostatic composition, areas of stromal expansion (SE) and areas that have both SE and epithelial hyperplasia (EH). B) The first graph shows percentage of mice with stromal expansion. The second graph shows the average area of stromal expansion as a percentage of the total measured area non-diabetic compared to diabetic mice. C) Percentage of mice with epithelial hyperplasia. While both non-diabetic and diabetic mice experience a similar percentage of stromal expansion, diabetic mice were more likely to exhibit epithelial hyperplasia. D) Immunohistochemical staining of BrdU in diabetic and non-diabetic male NOD mice reveals increased epithelial proliferation in diabetic NOD mice.