Table 2.
Univariate and multivariate analyses of disease-free survival
| Variables | Univariate analysis | Multivariate analysis | ||||
|---|---|---|---|---|---|---|
| HR | 95% CI | p-value | HR | 95% CI | p-value | |
| Agea | 0.98 | 0.95–1.01 | 0.140 | |||
| FIGO stage | 2.02 | 1.36–3.00 | < 0.001 | |||
| Tumor sizea | 1.43 | 1.14–1.08 | 0.002 | 1.37 | 1.06–1.77 | 0.015 | 
| Pelvic lymph node | 1.89 | 0.90–3.96 | 0.094 | |||
| Para-aortic lymph node | 4.21 | 1.89–9.40 | < 0.001 | 3.75 | 1.39–10.15 | 0.009 | 
| SCC antigena | 1.01 | 1.00–1.01 | 0.122 | |||
| pSUVmaxa | 1.04 | 0.99–1.08 | 0.086 | |||
| Nodal SUVmaxa | 1.07 | 1.04–1.11 | < 0.001 | 1.05 | 1.01–1.09 | 0.020 | 
| HPV negative | 2.37 | 1.01–5.55 | 0.047 | 3.68 | 1.44–9.41 | 0.007 | 
aAge, Tumor size, SCC antigen, pSUVmax, nodal SUVmax were analyzed as continuous variables. Hazard ratio represents the increase in hazard for each variable
HR hazard ratio, FIGO International Federation of Gynecology and Obstetrics, SCC squamous cell carcinoma, SUVmax maximum standardized uptake, pSUVmax SUVmax of primary tumor, nodal SUVmax SUVmax of the lymph node with the highest FDG uptake, HPV human papilloma virus