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. 2019 Jun 24;20:518. doi: 10.1186/s12864-019-5889-5

Table 2.

List of the genome-wide significant cis-eQTLs detected in the liver tissue (those that have been consistently detected in the muscle are shown in bold)1

liver cis-eQTL Gene
SSC N SNP Region (Mb) P-value q-value B δ ± SE A1 MAF Acronym Region (Mb)
1 15 H3GA0004318 251.1–254.7 8.56E-10 2.43E-05 2.43E-05 0.49 ± 0.07 A 0.281 HSDL2 253.1–253.1
1 1 ASGA0006805 253.4–253.4 9.61E-07 2.73E-02 2.73E-02 0.22 ± 0.04 C 0.411 CDC26 253.8–253.9
2 7 MARC0045154 4.6–8.8 2.63E-06 3.22E-02 7.47E-02 0.27 ± 0.06 A 0.146 CTSF 5.8–5.8
2 17 DIAS0003663 82.9–89.7 8.30E-09 1.18E-04 2.36E-04 0.30 ± 0.05 A 0.411 SERINC5 88.8–88.9
4 8 DIAS0000176 96.7–99.8 2.13E-07 2.27E-03 6.04E-03 0.30 ± 0.05 A 0.255 APH1A 98.8–98.8
5 1 H3GA0016032 19.8–19.8 8.25E-07 1.17E-02 2.35E-02 −0.38 ± 0.07 G 0.24 PPP1R1A 19.7–19.7
6 23 ALGA0116876 17.0–21.7 9.05E-16 0.00E+ 00 0.00E+ 00 0.86 ± 0.08 A 0.255 ARL2BP 19.2–19.2
6 13 MARC0031169 70.1–71.6 9.29E-07 3.30E-03 2.64E-02 −0.34 ± 0.04 G 0.276 LZIC 70.2–70.2
6 1 ASGA0104284 80.6–80.6 1.70E-06 4.82E-02 4.82E-02 −0.20 ± 0.04 C 0.141 ZNF436 81.2–81.2
6 14 ALGA0114962 82.1–89.0 6.79E-06 1.76E-02 1.93E-01 −0.32 ± 0.06 A 0.24 BSDC1 88.8–88.8
6 2 ASGA0030033 158.1–158.6 9.06E-07 2.57E-02 2.57E-02 −0.24 ± 0.04 G 0.328 YIPF1 158.4–158.4
7 2 DRGA0007123 9.9–10.4 5.49E-10 1.56E-05 1.56E-05 −0.40 ± 0.05 G 0.24 NOL7 9.9–9.9
8 13 ALGA0112294 10.6–11.3 3.37E-08 1.37E-04 9.58E-04 −0.36 ± 0.06 C 0.406 TAPT1 11.3–11.4
9 2 ASGA0094801 46.6–46.7 3.33E-06 4.73E-02 9.46E-02 −0.54 ± 0.10 G 0.266 THY1 46.6–46.6
10 1 ASGA0046443 10.2–10.2 4.07E-06 1.27E-02 1.16E-01 −0.25 ± 0.05 G 0.229 MARC2 10.1–10.1
10 10 ALGA0106385 48.1–54.6 1.22E-07 2.04E-03 3.46E-03 0.24 ± 0.04 G 0.396 KIAA1217 50.7–51.2
12 2 MARC0042683 24.1–24.7 5.74E-07 1.63E-02 1.63E-02 −0.30 ± 0.06 G 0.297 PNPO 24.1–24.2
12 3 M1GA0016795 42.8–43.1 1.61E-06 2.29E-02 4.58E-02 −0.32 ± 0.06 A 0.464 CRLF3 42.9–42.9
12 9 ALGA0066653 44.0–46.4 6.21E-12 9.00E-08 1.80E-07 0.31 ± 0.04 G 0.5 TMEM97 44.6–44.6
12 3 ALGA0066917 51.0–59.3 3.85E-06 3.65E-02 1.09E-01 0.19 ± 0.04 G 0.333 RABEP1 51.6–51.8
13 1 ALGA0070572 61.1–61.1 1.97E-06 2.80E-02 5.60E-02 −0.40 ± 0.07 A 0.474 ITPR1 61.0–61.3
13 6 ALGA0103755 141.3–148.9 1.73E-07 1.52E-03 4.92E-03 0.44 ± 0.06 A 0.286 GTPBP8 146.9–146.9
14 11 H3GA0038597 6.5–7.2 1.86E-09 4.94E-05 5.28E-05 −0.39 ± 0.06 A 0.401 POLR3D 6.5–6.5
14 22 H3GA0039048 10.1–14.0 8.60E-11 4.10E-07 2.44E-06 0.35 ± 0.05 G 0.469 HMBOX1 12.6–12.8
14 2 DRGA0013801 42.7–43.4 2.70E-07 7.66E-03 7.66E-03 −0.33 ± 0.06 A 0.406 GRK3 43.3–43.4
14 2 ASGA0065623 100.9–100.9 1.21E-06 1.24E-02 3.43E-02 0.37 ± 0.07 A 0.234 LIPA 101.1–101.2
16 5 ALGA0088786 5.7–5.8 1.04E-07 9.88E-04 2.96E-03 0.61 ± 0.10 G 0.406 RETREG1 5.7–5.8
18 8 ASGA0100292 0.2–2.3 4.33E-06 3.08E-02 1.23E-01 −0.15 ± 0.03 A 0.234 ESYT2 0.5–0.6

1SSC: porcine chromosome, N: Number of SNPs significantly associated with the trait under study, SNP: SNP displaying the most significant association with the trait under study, Region (Mb): region containing SNPs significantly associated with the trait under study, P-value: nominal P-value, q-value: q-value calculated with a false discovery rate approach, B: Bonferroni corrected P-values, δ: allelic effect and its standard error (SE), A1: minority allele, MAF: frequency of the minority allele