Table 2.
liver cis-eQTL | Gene | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|
SSC | N | SNP | Region (Mb) | P-value | q-value | B | δ ± SE | A1 | MAF | Acronym | Region (Mb) |
1 | 15 | H3GA0004318 | 251.1–254.7 | 8.56E-10 | 2.43E-05 | 2.43E-05 | 0.49 ± 0.07 | A | 0.281 | HSDL2 | 253.1–253.1 |
1 | 1 | ASGA0006805 | 253.4–253.4 | 9.61E-07 | 2.73E-02 | 2.73E-02 | 0.22 ± 0.04 | C | 0.411 | CDC26 | 253.8–253.9 |
2 | 7 | MARC0045154 | 4.6–8.8 | 2.63E-06 | 3.22E-02 | 7.47E-02 | 0.27 ± 0.06 | A | 0.146 | CTSF | 5.8–5.8 |
2 | 17 | DIAS0003663 | 82.9–89.7 | 8.30E-09 | 1.18E-04 | 2.36E-04 | 0.30 ± 0.05 | A | 0.411 | SERINC5 | 88.8–88.9 |
4 | 8 | DIAS0000176 | 96.7–99.8 | 2.13E-07 | 2.27E-03 | 6.04E-03 | 0.30 ± 0.05 | A | 0.255 | APH1A | 98.8–98.8 |
5 | 1 | H3GA0016032 | 19.8–19.8 | 8.25E-07 | 1.17E-02 | 2.35E-02 | −0.38 ± 0.07 | G | 0.24 | PPP1R1A | 19.7–19.7 |
6 | 23 | ALGA0116876 | 17.0–21.7 | 9.05E-16 | 0.00E+ 00 | 0.00E+ 00 | 0.86 ± 0.08 | A | 0.255 | ARL2BP | 19.2–19.2 |
6 | 13 | MARC0031169 | 70.1–71.6 | 9.29E-07 | 3.30E-03 | 2.64E-02 | −0.34 ± 0.04 | G | 0.276 | LZIC | 70.2–70.2 |
6 | 1 | ASGA0104284 | 80.6–80.6 | 1.70E-06 | 4.82E-02 | 4.82E-02 | −0.20 ± 0.04 | C | 0.141 | ZNF436 | 81.2–81.2 |
6 | 14 | ALGA0114962 | 82.1–89.0 | 6.79E-06 | 1.76E-02 | 1.93E-01 | −0.32 ± 0.06 | A | 0.24 | BSDC1 | 88.8–88.8 |
6 | 2 | ASGA0030033 | 158.1–158.6 | 9.06E-07 | 2.57E-02 | 2.57E-02 | −0.24 ± 0.04 | G | 0.328 | YIPF1 | 158.4–158.4 |
7 | 2 | DRGA0007123 | 9.9–10.4 | 5.49E-10 | 1.56E-05 | 1.56E-05 | −0.40 ± 0.05 | G | 0.24 | NOL7 | 9.9–9.9 |
8 | 13 | ALGA0112294 | 10.6–11.3 | 3.37E-08 | 1.37E-04 | 9.58E-04 | −0.36 ± 0.06 | C | 0.406 | TAPT1 | 11.3–11.4 |
9 | 2 | ASGA0094801 | 46.6–46.7 | 3.33E-06 | 4.73E-02 | 9.46E-02 | −0.54 ± 0.10 | G | 0.266 | THY1 | 46.6–46.6 |
10 | 1 | ASGA0046443 | 10.2–10.2 | 4.07E-06 | 1.27E-02 | 1.16E-01 | −0.25 ± 0.05 | G | 0.229 | MARC2 | 10.1–10.1 |
10 | 10 | ALGA0106385 | 48.1–54.6 | 1.22E-07 | 2.04E-03 | 3.46E-03 | 0.24 ± 0.04 | G | 0.396 | KIAA1217 | 50.7–51.2 |
12 | 2 | MARC0042683 | 24.1–24.7 | 5.74E-07 | 1.63E-02 | 1.63E-02 | −0.30 ± 0.06 | G | 0.297 | PNPO | 24.1–24.2 |
12 | 3 | M1GA0016795 | 42.8–43.1 | 1.61E-06 | 2.29E-02 | 4.58E-02 | −0.32 ± 0.06 | A | 0.464 | CRLF3 | 42.9–42.9 |
12 | 9 | ALGA0066653 | 44.0–46.4 | 6.21E-12 | 9.00E-08 | 1.80E-07 | 0.31 ± 0.04 | G | 0.5 | TMEM97 | 44.6–44.6 |
12 | 3 | ALGA0066917 | 51.0–59.3 | 3.85E-06 | 3.65E-02 | 1.09E-01 | 0.19 ± 0.04 | G | 0.333 | RABEP1 | 51.6–51.8 |
13 | 1 | ALGA0070572 | 61.1–61.1 | 1.97E-06 | 2.80E-02 | 5.60E-02 | −0.40 ± 0.07 | A | 0.474 | ITPR1 | 61.0–61.3 |
13 | 6 | ALGA0103755 | 141.3–148.9 | 1.73E-07 | 1.52E-03 | 4.92E-03 | 0.44 ± 0.06 | A | 0.286 | GTPBP8 | 146.9–146.9 |
14 | 11 | H3GA0038597 | 6.5–7.2 | 1.86E-09 | 4.94E-05 | 5.28E-05 | −0.39 ± 0.06 | A | 0.401 | POLR3D | 6.5–6.5 |
14 | 22 | H3GA0039048 | 10.1–14.0 | 8.60E-11 | 4.10E-07 | 2.44E-06 | 0.35 ± 0.05 | G | 0.469 | HMBOX1 | 12.6–12.8 |
14 | 2 | DRGA0013801 | 42.7–43.4 | 2.70E-07 | 7.66E-03 | 7.66E-03 | −0.33 ± 0.06 | A | 0.406 | GRK3 | 43.3–43.4 |
14 | 2 | ASGA0065623 | 100.9–100.9 | 1.21E-06 | 1.24E-02 | 3.43E-02 | 0.37 ± 0.07 | A | 0.234 | LIPA | 101.1–101.2 |
16 | 5 | ALGA0088786 | 5.7–5.8 | 1.04E-07 | 9.88E-04 | 2.96E-03 | 0.61 ± 0.10 | G | 0.406 | RETREG1 | 5.7–5.8 |
18 | 8 | ASGA0100292 | 0.2–2.3 | 4.33E-06 | 3.08E-02 | 1.23E-01 | −0.15 ± 0.03 | A | 0.234 | ESYT2 | 0.5–0.6 |
1SSC: porcine chromosome, N: Number of SNPs significantly associated with the trait under study, SNP: SNP displaying the most significant association with the trait under study, Region (Mb): region containing SNPs significantly associated with the trait under study, P-value: nominal P-value, q-value: q-value calculated with a false discovery rate approach, B: Bonferroni corrected P-values, δ: allelic effect and its standard error (SE), A1: minority allele, MAF: frequency of the minority allele