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. 2019 Jun 24;18:213. doi: 10.1186/s12936-019-2846-3

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© The Author(s) 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — Plasmodium chabaudi parasitaemia in mice treated or not with captopril, chloroquine or both drugs (n = 6). a Blood parasitaemia of infected groups with vehicle solution (INF), captopril (CP), chloroquine (CQ), chloroquine and captopril association (CQ CP) (n = 6). b Survival curve of each animal group showed in A (n = 6). c ACE activity measured with Abz-FRK(Dnp)P-OH in blood plasma from mice of infected groups with vehicle solution (INF) or treated with CP. (n = 3). One-way ANOVA with multiple comparison post-test of Bonferroni’s; *p < 0.05, compared with the respective control of treatment (INF, without CP)