Fig. 3.

Heart rate variability indexes and arrhythmia evaluation. Heart rate variability parameters and spontaneous arrhythmic events in CTRL (triangles) and TiO₂-NP (square) groups. a SDRR duration (ms). b r-MSSD duration (ms). c Sinus pauses (SP, number of events). d Atrio-ventricular blocks (AV block, number of events). Kruskal-Wallis (post hoc analyses: Dunn’s multiple comparison’s) was performed and statistical significance was set at p < 0.05. ● vs CTRL; * vs corresponding 1° week; # vs corresponding 3° week; § vs corresponding 6° week. Data are represented as median and IQR