Table 2. In vitro susceptibility test results of 20 Fonsecaea nubica strains to Terbinafine and Amphotericin B.
| MIC (μg/mL) | FICI | ||||||||||
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| GM of single drug | MIC50 of single drug | MIC90 of single drug | Range of single drug | Range of drug in combination | Range | GM | |||||
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| TBF | AMB | TBF | AMB | TBF | AMB | TBF | AMB | TBF | AMB | ||
| 0.167 | 3.138 | 0.25 | 2 | 0.5 | 16 | 0.0313-0.5 | 0.5-16 | 0.0078-0.125 | 0.125-4 | 0.19-0.5 | 0.36 |
FICI: fractional inhibitory concentration index (values were interpreted as follows: FICI≤0.5, synergism; 0.5<FICI≤4, indifference; and FICI > 4, antagonism); MIC: the minimal inhibitory concentration; GM: geometrical mean; TBF: terbinafine; AMB: amphotericin B.