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. 2019 Jun 19;12:4779–4788. doi: 10.2147/OTT.S203235

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© 2019 Luo et al.

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Knockdown of H19 downregulates WNT1 expression. (A) Online starBase database showed that H19 and WNT 3ʹUTR contain the binding sites of miR-22-3p. (B) Knockdown experiment suggested that downregulation of H19 increased the levels of miR-22-3p expression (C, D) Knockdown of H19 significantly decreased WNT1 expression at both the mRNA and protein levels in KYSE150R cells. *P<0.05.