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. 2019 May 31;9(14):3992–4005. doi: 10.7150/thno.32715

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(A) Fluorescence images of nude mice at different time points after administration of free Ce6 and MSNR@MoS₂-HSA/Ce6; the right panel shows the ex vivo images examined at 24 h. (B) Average fluorescence signals of Ce6 in major organs examined at 24 h. (C) MSOT images of 4T1 tumor-bearing mice after being intravenously injected with MSNR@MoS₂-HSA/Ce6. (D) Photoacoustic intensity linearly fit to the concentration of MSNR@MoS₂-HSA/Ce6 aqueous solutions; inset: the corresponding PA images. (E) CT images of tumor site before and after intratumor injection with MSNR@MoS₂-HSA/Ce6. (F) Corresponding HU value of MSNR@MoS₂-HSA/Ce6 nanocomposites in the tumor before injection and 12 h after injection.