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Ro 4-1284 co- and/or posttreatment does not affect 3, 4-methylenedioxymethamphetamine (MDMA)-induced hyperthermia. Body temperature was recorded using temperature data-loggers implanted in the intraperitoneal cavity. A, 20 mg/kg MDMA dose. B, 27.5 mg/kg MDMA dose. Results are expressed as means ± SE (n = 3–9) and represent temperature measurements collected from all 4 treatment groups.
