Table 4. Illustrates the comparison between molecular analysis (KRAS or KRAS/GNAS) and cytology analysis for detection of a precursor mucinous pancreatic cystic lesion.

Gene	KRAS	KRAS or GNAS	Cytology analysis
Number of cases	(303)	(182)a	(309)
Sensitivity:	82.4%*	93.3%*	43.5%
Specificity:	93.4%	83.9%	100%
PPV:	90.7%	84.7%	100%
NPV:	87.0%	92.9%	65.9%

^*Sensitivity of molecular analysis is significantly higher than cytology (p = 0.0001).

^a182 cases were tested by NGS for both KRAS and GNAS genes.