Table 1.

HITSystem 2.0 intervention components. Expected timing, dose, and target of alerts and SMS (short message service) texts to providers and HIV positive pregnant women.

Actors	Actions	Timing	Dosea	Target
Hospital-based providers; providers	Algorithm-driven electronic alerts	When PMTCTb service late/missing (enrollment-infant EIDc link)	Avg=8 per mom, range=0 to 14+	PMTCT quality: complete PMTCT retention (pregnancy to EID link)
Lab-based providers; lab techs	Algorithm-driven electronic alerts	When receipt of VLd sample or VL results delayed	Avg=1 per mom, range=0-2+	PMTCT efficiency: reduced turn-around time for key PMTCT services
HIV-positive pregnant women	Algorithm-driven electronic SMS text messages	Appointment reminders (2 days before appointment); adherence reminders (daily, weekly, biweekly, monthly); facility-based delivery reminders (4 and 2 weeks before EDDe)	Avg=4 per mom, range=0-8+; avg=20 per mom, range=0-245+; avg=2 per mom, range=2 to 2	PMTCT quality and PMTCT efficiency

^aDose represents anticipated study averages and ranges only, assuming one alert per alert type per pregnancy. Actual dose will depend on client-specific factors such as gestational age at enrollment, adherence to PMTCT guidelines and scheduled services, and frequency preferences for adherence reminders.

^bPMTCT: prevention of mother-to-child transmission of HIV.

^cEID: early infant diagnosis.

^dVL: viral load.

^eEDD: estimated due date.