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. 2019 Jun 25;16(6):e1002834. doi: 10.1371/journal.pmed.1002834

Table 4. Association of self-reported educational attainment with CVD and risk factors, with state fixed effects (OLS analysis).

Outcome HRS NHANES
Coefficient for 1 Year of Education Coefficient for More than High Schoola Coefficient for More than High Schoola
Self-reported
 Hypertension −0.0083** −0.058** −0.048**
(−0.010 to −0.0064) (−0.072 to −0.044) (−0.059 to −0.037)
 Diabetes −0.010** −0.080** −0.042**
(−0.013 to −0.0082) (−0.095 to −0.065) (−0.050 to −0.034)
 Heart disease −0.0094** −0.066**
(−0.011 to −0.0078) (−0.080 to −0.052)
 Smoking −0.017** −0.12** −0.17**
(−0.020 to −0.014) (−0.13 to −0.100) (−0.18 to −0.15)
 Depression −0.027** −0.19**
(−0.029 to −0.024) (−0.21 to −0.17)
Anthropometric
 BMI −0.12** −0.84** −0.26**
(−0.15 to −0.099) (−0.98 to −0.71) (−0.43 to −0.084)
 Blood pressure −0.63** −4.00** −2.47**
(−0.80 to −0.46) (−5.11 to −2.89) (−3.01 to −1.92)
Biomarkers
 Hyperglycemia −0.0071** −0.053** −0.050**
(−0.0094 to −0.0049) (−0.073 to −0.034) (−0.063 to −0.038)
 Total cholesterol 0.12 0.37 0.56
(−0.19–0.43) (−2.00–2.73) (−0.61–1.72)
 HDL cholesterol 0.45** 2.39** 2.48**
(0.32–0.57) (1.62–3.17) (2.01–2.95)
 LDL cholesterol −1.90
(−4.31–0.52)
 Ln(Triglycerides) −0.11**
(−0.13 to −0.087)
 Ln(CRP) −0.049** −0.29** −0.20**
(−0.056 to −0.041) (−0.34 to −0.24) (−0.24 to −0.15)
 Ln(Telomere length) 0.0036* 0.019 0.014**
(0.00071–0.0065) (−0.0043–0.043) (0.0077–0.021)

aReference: less than high school.

*p < 0.05.

**p < 0.01.

Confidence interval (95%) in parentheses. The primary predictor variable in HRS is a continuous variable for self-reported educational attainment in years. For NHANES, the primary predictor is the “more than high school” category of educational attainment (reference: less than high school), as NHANES does not include a continuous variable for education in all survey waves. A similar analysis with a categorical exposure variable was carried out in HRS for comparability. Analyses involved linear models using OLS, with robust standard errors clustered by state. All models adjust for individual-level gender, race, and year of birth and state-level percent urban, percent foreign born, percent black, manufacturing wages, and manufacturing jobs per capita.

Abbreviations: CRP, C-reactive protein; CVD, cardiovascular disease; HDL, high-density lipoprotein; HRS, Health and Retirement Study; LDL, low-density lipoprotein; NHANES, National Health and Nutrition Examination Survey; OLS, ordinary least squares.