Table 1. Demographics and clinical characteristics of HIV+ subjects stratified by TB status.
| Characteristics | TB Patients (n = 74) |
Non-TB Patients (n = 30) |
P* |
|---|---|---|---|
| Male sex (%) | 27 (36) | 11 (37) | 1 |
| Age, median years [25%ile, 75%ile] |
33 [28, 38] |
31 [27, 36] |
0.19 |
| Current smoker (%) | 15 (20) | 6 (20) | 1 |
| Previous TB (%) | 14 (19) | 0 | 0.009 |
| CD4, median cells/mm3 [25%ile, 75%ile] |
138 [60, 204] |
135 [80, 201] |
0.94 |
| Abnormal CXRa (%) | 53 (75) | 9 (32) | 0.0002 |
| Initial sputum AFB smear positive (%) | 19 (26) | 0 | 0.001 |
| Two sputa combined AFBb smear positive (%) | 23 (31) | 0 | 0.0002 |
| Initial sputum GeneXpert positive (%) | 42 (57) | 0 | <0.0001 |
| Two sputa combined GeneXpert positive (%) | 52 (70) | 0 | <0.0001 |
| U-LAM dipstick+ (%) | 22 (30) | 0 | 0.0003 |
| U-LAM ELISA+ (%) | 21 (28) | 0 | 0.0004 |
| TB home contact | 1 (1) | 3 (10) | 0.07 |
| Symptoms present at evaluation: | |||
| Cough | 48 (65) | 10 (33) | 0.005 |
| Hemoptysis | 2 (3) | 1 (3) | 1 |
| Shortness of breath | 32 (43) | 3 (10) | 0.001 |
| Night sweats | 40 (54) | 9 (30) | 0.03 |
| Fever | 22 (30) | 7 (23) | 0.63 |
| Weight loss | 62 (84) | 18 (60) | 0.019 |
*P-values for categorical variables are given using the Fisher’s exact test and for continuous variables using the Mann-Whitney U test;
a: CXR: chest X-ray;
b: AFB: acid fast bacilli