Table 3. Baseline 12, 24, 36 month 6MWT values (range, mean and median) subdivided according to genotype and age.
| AGE | 6MWT | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Subgroups by skipping | MIN | MEAN | MEDIAN | MAX | Baseline | 12 months |
24 months |
36 months |
12 month changes | 24 month changes | 36 month changes | |
|
Study cohort (n:97) |
44 (n:24) | 3.32 | 7.48 | 7.23 | 14.30 | 402.25 | 406.09 | 412.00 | 359.21 | 3.85 | 9.75 | -43.04 |
| 45 (n:27) | 4.36 | 7.86 | 8.01 | 12.12 | 377.27 | 349.99 | 337.48 | 326.42 | -27.28 | -39.79 | -50.85 | |
| 51 (n:18) | 4.00 | 8.38 | 8.80 | 11.53 | 400.46 | 353.56 | 313.72 | 253.11 | -46.90 | -86.73 | -147.34 | |
| 53 (n:28) | 4.12 | 8.14 | 8.55 | 11.60 | 359.46 | 330.49 | 294.31 | 190.93 | -28.97 | -65.15 | -168.54 | |
| <7 years (n:33) | 44 (n:12) | 3.32 | 5.45 | 5.78 | 6.90 | 388.66 | 411.28 | 446.82 | 420.67 | 22.62 | 58.16 | 32.01 |
| 45 (n:9) | 4.36 | 5.56 | 5.55 | 6.83 | 384.13 | 390.05 | 416.30 | 442.13 | 5.92 | 32.18 | 58.00 | |
| 51 (n:3) | 4.00 | 4.56 | 4.08 | 5.60 | 386.83 | 415.67 | 441.67 | 437.33 | 28.83 | 54.83 | 50.50 | |
| 53 (n:9) | 4.12 | 5.33 | 5.20 | 6.07 | 359.89 | 373.01 | 353.56 | 261.89 | 13.12 | -6.33 | -98.00 | |
| ≥ 7 years (n:64) | 44 (n:12) | 7.57 | 9.52 | 9.10 | 14.30 | 415.83 | 401.33 | 377.18 | 297.75 | -14.50 | -38.65 | -118.08 |
| 45 (n:18) | 7.00 | 9.45 | 9.33 | 12.12 | 372.56 | 327.46 | 279.68 | 246.88 | -45.09 | -92.88 | -125.68 | |
| 51 (n:15) | 7.00 | 9.15 | 9.14 | 11.53 | 403.18 | 341.13 | 288.13 | 216.27 | -62.05 | -115 | -187 | |
| 53 (n:19) | 7.00 | 9.47 | 9.76 | 11.60 | 359.26 | 310.35 | 264.69 | 157.32 | -48.91 | -95 | -202 | |