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. 2019 Jun 13;15(6):e1008158. doi: 10.1371/journal.pgen.1008158

Fig 1. Enhanced activity of PDF-expressing neurons reduces dormancy levels.

Fig 1

(A) Hypersensitization of PDF+ neurons (Pdf>Na+ChBac) and overexpression of PDF (Pdf>Pdf) both result in a significant reduction of reproductive arrest. (B) Pan-neuronal overexpression of sNPF (elav>2xsNPF) leads to a significant decrease in the proportion of arrested females. (C) Overexpression of sNPF in the PDF-expressing neurons (Pdf>2xsNPF) and in the small ventrolateral neurons (R6>2xsNPF) triggers females to exit from dormancy. Numbers within bars refer to the number of dissected females considered in the dormancy assays. Data are presented as mean ± SEM. ANOVA on arcsine transformations, followed by post-hoc Tukey HSD test. ***p<0.001, n.s. not significant.