Table 1B.
CLFB-1134 (Single-dose) Pharmacokinetic Properties in Sprague-Dawley Rats
| IP Dose 10mg/kg *30% solutol in saline |
|
|---|---|
| PLASMA | |
| AUC | 5630 |
| T ½ (hr) | 2.5 |
| CLZ (mL/hr/kg) | 1775 |
| Cmax | 2135 |
| Tmax | 0.25 |
| BRAIN | |
| AUC | 2870 |
| T ½ (hr) | 3.6 |
| Cmax | 517 |
| Tmax | 2 |
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